We have the experience in tableting, coating and packaging required for successful mini-tablet development. We also understand how to fill mini-tablets in capsules and how to adapt them for use in dispensing equipment.
Mini-tablets, which are characterised by their reduced diameter of about 2-3 mm, have many applications. Their small size makes them very easy to swallow and allows dose flexibility. Additionally, functional coatings can be applied in order to achieve modified release of active drugs.
These formulations are ideal for delivering fixed dose combinations. One type of mini-tablet can be mixed with another or with pellets, granules or powders and then filled into a capsule in order to avoid incompatibilities in combination products. This process can also be used to achieve advanced drug release profiles. Mini-tablets for multiple unit modified release applications allow a higher drug loading than drug layering on an inert core.
In principle, the development and manufacture of mini-tablets is similar to the development and manufacture of larger tablets. However, successful development of mini-tablets requires specialist expertise as many drug development issues are enhanced due to their small size.
Our experienced team can develop mini-tablet products to your individual requirements and perform tech transfer into commercial manufacture.