Auto-injectors: Through Thick and Thin
A prominent trend within the pharmaceutical industry in recent years has been the increased instance of new medications that require parenteral delivery. As the injectable market continues to grow, so does the trend for patients to administer medication themselves. However, as many new injectable drug products being developed are tending towards high viscosity formulations, this constitutes a potential problem for the administration of these drugs using the preferred self-administered delivery device; the auto-injector.
One of the main challenges to overcome when developing parenteral products for self-administration is ensuring that the formulation is delivered in a patient friendly way.
Devices with more compact energy sources using liquified gas present a potential alternative to the traditional spring-based devices by reducing the risk of damage to the primary container when experiencing high impact forces released during administration of high-viscosity formulations as well as allowing greater flexibility in achieving desired performance characteristics. Furthermore, novel syringes that are resistant to the high forces experienced will likely also be required.
In an article with The Medicine Maker, our Global Business Development Director, Hans Jensen, discusses more on the key challenges for the development of parenteral products and provides insight on potential ways to overcome them.
Click the link here to read more.